Wednesday, February 24, 2010
A Bit of a Personal Rant.
Have people lost their minds? According to Dr. Free-Ride, protesters have showed up at Ringach's home in masks at night traumatizing his family. I couldn't find how old his children are but can you image (if they're younger) the damage this could have emotionally, mentally and socially on his children? How is targeting one man's entire family for what they believe to be "corrupt action on HIS part" not equally brutal and gruesome? They refer to the primates as "innocent beings..." HELLO?! Are CHILDREN NOT innocent beings?!
Sober up!
That didn’t happen for me. In fact, nothing happened at all; I completely missed my 21st. I was so busy studying for two exams, writing a paper, and finishing a lab report that I worked right through mine. I didn’t catch on until two days later when I checked my mail and found the birthday card from my mom:
Intent on rectifying this on my 22nd, I realized I would need a way to sober up quick to be ready to help run the sign-in at a high school math competition at 8AM the next morning.
I was wracking my brains, and then five minutes ago, I remembered the Sober Up Techniques episode of Mythbusters.
We’ve all had an occasion where we need to sober up. But what is the best way? Is this it? Have I found the magic bullet?
Unfortunately, if I’m remembering correctly, this wasn’t the best method. I guess I’m stuck with black coffee.
Science is fun again.
Tuesday, February 23, 2010
Polar Bears like to play
Finding a video about something interesting in science was kind of challenging for me. So when all else fails I like to research my high school mascot the polar bear. Polar bears are large creatures that appear very scary. How scary can these somewhat cute animals be? Well it depends if your a husky trying to have some fun with a large bear. When I saw this video it was unbelievable.http://www.youtube.com/watch?v=iHj82otCi7U
Avian Flu Concerns
http://www.nature.com/nature/journal/v462/n7276/full/462986a.html
Monday, February 22, 2010
Heil...?
In summary, the article is exposing the recent rise in genetic testing as part of routine prenatal studies and how it’s almost eradicating many inherited diseases like Tay-Sach’s, dysautonomia and cystic fibrosis.
Marilynn Marchione, the author, looks at many numbers—the number of babies born with these diseases, percentages of decreases, amount of couples being tested. One huge factor she stumbles on (really it’s a minor note in the article) is screening embryos. I’d never heard of this and a description in the article is lacking (that’s issue #2) so I did some research. In-vitro fertilization is performed and when the embryo reaches the eight-cell mark, a single cell is removed and the DNA analyzed. If one or more disease-associated genetic alteration is found, that embryo is terminated. Only embryos without mutations are implanted into the womb. In some rare cases, individuals who choose to screen decide to go “all-out” choosing not only a mutation-free embryo but also one with a particular hair or eye color. Legal? Yes. Ethical?... Marchione briefly mentions eugenics and selective breeding after addressing “hot button issues” like abortion and embryo destruction which she returns to later in the article. But not eugenics. Not only does she not revert back to it later, she never describes what it is, so here goes: eugenics is the study or belief in a master race; undergoing “…measures to improve the innate humankind…solv[ing] the problems which face our species” as the Future Generations website claims. But is it right? Sure, eradicating diseases like cystic fibrosis and thalassemia may be a good thing but a “master race?” Improving future generations through genetic screening for higher intelligence and moral character? Can you screen for that? Regardless, is it ethical to select for particular traits, say, blond hair + blue eyes (shameful Hitler reference, sorry). I think Dr. Barron Lerner, a Columbia University medical historian hit the nail on the head: “If a society is so willing to screen aggressively to find these genes and then to potentially to have abort the fetuses, what does that say about the value of the lives of those people living with the disease?”
My mom highlighted a number of things in the articles and sticky-noted questions she had. Most of her questions asked what the author was talking about—genetic testing and embryo screening, which had little to no description of how these procedures were being done. At the very end, my clever madre stickey-noted, “wouldn’t there just be different mutations later on?” STOP. THINK. If the world eradicated the aforementioned inherited diseases, would there just be different, potentially worse mutations later on? Better yet, how would we test for them? Are we selecting for a master race or a race of potentially worse, undetectable mutations? What is considered a mutation worthy of abortion?
Looking at a personal example: Red hair. There’s less than 5% of natural redheads left in the world. Perhaps it’s our higher rate of anemia (losing iron to our hair?) or the need for a higher dose of anesthesia (survival of the fittest)? Regardless, in 2005, many scientists believed that by 2100 a natural redhead would be hard to come-by, if not extinct. UNTIL eugenics. Selecting for red hair? Selecting for anemia? I’m not saying I agree or disagree with this process. Eradicating inherited diseases sounds great but will it have more horrible consequences? Better yet, are we selecting for things without knowing how they’ll effect society as a whole? Will the world end up Blond haired and blue eyed like Hitler wanted?
References
http://www.nature.com/scitable/topicpage/Embryo-Screening-and-the-Ethics-of-60561
http://dictionary.reference.com/browse/eugenics
http://www.eugenics.net/
http://community.seattletimes.nwsource.com/archive/?date=20050509&slug=redhair09
http://chronicle.northcoastnow.com/2010/02/21/
The Wonders of Caves
You may be wondering if going into the depths of the cave can actually be bad for the creatures. Well, in reality it is. However, the tour guides do a wonderful job of letting people know where to walk and where not to walk. For example, there was some water we were able to walk through, but they did take us near water that was not allowed to be touched due to the unique species living in the water. The guides even ask people who may have been to other caves that have the white-nose syndrome to not go on the trip. As of now, Mammoth Cave bats do not have the syndrome that is killing their relatives. I think that in situations like that, people respect where they are. The guides also love the environment they are in and I think that if their system did not work, they probably would not still have the tour. It normally seems like people don't have respect for their environment until they see it hands-on.
Anyway, I found a cave diving video that I think is really cool. I want to see the entire episode! If you're a BBC fan, I think you'll enjoy it.
If you want more information on the biology of caves or the white-nose syndrome, check out:
(1) http://www.nps.gov/archive/seki/snrm/wildlife/cave_biology.htm
(2) http://www.fws.gov/northeast/white_nose.html
Look At That Tongue!
I know it sounds crazy because what American-born female hates butterflies but keep in mind I'm a biology major and Ashland requires you take zoology (or botany) and this is forever my image of butterflies:
What you're looking at is a scanning electron microscope image of a pyralidae moth. Moths and butterflies belong to the order Lepidoptera meaning their wings are covered with scales.(1) Both have similar physical appearance and life cycles, however moths are more active at night, typically more boring in color and tapered, straight antennae.
Almost all Lepidoptera have the coiled proboscis (seen above) as a feeding mechanism. The tube extends into the flower for sucking up nectar and is controlled by a sac inside the head. Through contraction and expansion (similar to the human diaphragm) the butterfly can suck up nectar.
If I hate them so much why am I researching them? Because Observations of a Nerd tackle my intrigue. A recent post as can be seen at the link at the bottom addressed the parasitic wasp, which if anyone reading this was in Evolution you'd know Dr. Greene made quite the to do over them. These wasps lay their eggs inside other animals which then hatch and grow, feeding on the host from the inside out. Finally, like something from alien they burst out of the host to go spread their evil. Two particular species mentioned Trichogramma brassicae and Trichogramma evanescens smell the chemicals used during butterfly mating to stalk and murder their prey. Butterflies secrete chemicals during mating to ward off other males from a recently impregnated female. These wasps sense those chemicals and stalk the butterflies to their egg location where they attack. The most amazing part is that they stalk so incredibly closely. They actually climb aboard the disgusting mouthparts of the butterfly and ride with them to their egg-stash. Clever little "spies" as they're popularly called. I guess it doesn't pay to have a long gangly-tongue?
http://scienceblogs.com/notrocketscience/2010/02/parasitic_wasps_hitchhike_on_butterflies_by_smelling_for_che.php
(1)http://butterflywebsite.com/
Saunas: good or bad?
Fast forward by fifteen minutes. There I was, sweating my Charlie Browns off. As my eyes started to feel like eggs frying on the sidewalk, I started wondering what possible benefit this legalized torture could possibly have. That was when I decided that I would use my fourth blog post to get some answers. Which was difficult to do, since the next morning I had a massive migraine. I blame the sauna.
First, I tried Youtube and found this subtly creepy video about sauna health benefits.
All he mentioned was that saunas are good for people with Arthritis and your immune system.
Since that wasn’t much help, I kept searching. Then I found this website by the North American Sauna Society.
They mention these health benefits:
- Improved circulation
- Lower blood pressure
- Cardiovascular health (gives your heart a mini-workout)
- Increased resistance to illness
- Relieves congestion
- Removes toxins and impurities
- Reduces pain from sunburn
- Relieves tension, stress, and mental fatigue
- Better and more restful sleep
- Burns calories
- Maintains clear and healthy skin
- Helps with kidney function
You should avoid using the sauna if you have any of these complications:
- Heart disease
- High blood pressure
- Asthma
- Skin condition
- Running a fever
- Inflammatory disease
- An injury
- Contagious disease
Other notes:
- Moderate sauna use is safe for pregnant women
- Sauna use will not cure a hangover (damnit!)
Well, that’s all I found. I see why people use the sauna now, but I think I prefer the hot tub, thanks.
Wednesday, February 17, 2010
The History of Denialism
Tuesday, February 16, 2010
Denialism or Insanity
Monday, February 15, 2010
Denialism and Global Warming
- Wikipedia
The topic this week in our Biology Senior Seminar course is Denialism. More specifically, Science Denialism. As the all-knowing Wikipedia stated, this is when the obvious truth, supported by evidence, is ignored or deemed false for a variety of reasons, or as a natural defense mechanism against what makes us uncomfortable.
Many days went by as I tried to think of something to post that would address the topic of Science Denialism. Then Friday night rolled around and I took the night off at my favorite pub. Around four in the afternoon on Saturday, I felt up to the task of doing deep thinking and research again.
Unfortunately, I got sidetracked because my car was barely visible under all the snow from the past two snowstorms. Since I’m not dumb enough to drive to/from the pub (I walk instead), multiple snow plows to clear the parking lot had all but buried my poor car.
As I went to work with nothing but my window scraper to aid me, I realized just how much time and effort it was going to take to free my car. An hour later and deeply annoyed, I wondered aloud, “I thought Al Gore said it was supposed to be getting WARMER!”
That was when I realized I had found the topic for my third blog post:
The Denialism of Global Warming.
I admit that, up to about two years ago, I too thought that Global Warming was just a bleeding-heart scare tactic cooked up by the Hippies. And movies I couldn’t stand such as An Inconvenient Truth, when viewed alongside stats about Al Gore’s house, didn’t help their case in my mind. Then about two years ago, I actually started looking at the scientific evidence for Global Warming, and was reeling in shock. I mean, 677079 pieces of evidence? My entire world was shattered – why had I not listened to the wise scientists, when I myself aspired to be one?
One aspect of the Science Denialism problem that I see constantly is that our society is VERY divided on the issue of science. There is a group of people out there who absolutely refuse to listen to scientists or scientific reasoning. One group sees science as a group of people diligently working on ways to help improve and explain parts of everyday life. The other group sees science as an evil group of corporations and government agents working with crazed, labcoat-wearing loonies who delight in abusing animals and stabbing us with sharp syringes.
The first group views scientists and their work as helpful to the general welfare of mankind (see Jonas Salk).
The other group sees scientists as soulless fiends hell-bent on destroying the world along with everything we hold dear, and scientific ideas as immoral doctrines of evil (see the controversy around genetically modified foods).
Needless to say, the first group openly accepts science, while the second group vehemently rejects and opposes it.
The problem of Science Denialism comes in when we refuse to listen to EVERYTHING scientists are saying solely because we disagree with them about ONE thing they say. Take my example: Since I believed Al Gore to be a hypocrite and saw An Inconvenient Truth as his accidental claim to fame, I immediately dismissed everything he was associated with (such as Global Warming) as a crock.
The best way to correct Science Denialism is to explain the benefits of science in a way anyone can understand. That is, after all, one of the reasons we started this blog in the first place: to communicate what science has to offer to the common net-surfer. People won’t freak out as much about science if we communicate its ideas in an effective way. By making it more easily accessible and understandable, it won’t be as scary to people who oppose it as some faceless evil that must be fought and destroyed. And we should also put some effort into having a credible spokesperson, too.
The best way to communicate science effectively would be to follow this handy list:
- Use popular media (such as blogs or Wikipedia) to discuss and explain scientific facts, history, and concepts. Ever since we started our blogs, I found that I enjoy reading them more and more. And the more I read, the more I learn. For me, blogs are a treasure-trove of untapped scientific news and information. If we keep science to ourselves, locked away in the Ivory Tower, no wonder people know nothing about it. And what we know little about, we fear and reject. We avoid the dark, scary basement…until we turn on the light and realize it is very beneficial to go down there (especially if we have three weeks of laundry to do that we ignored).
- Use recognizable, trustworthy spokesmen to make the personal study of science more acceptable. Who would you believe when told how great the pursuit of scientific knowledge is: Adolf Hitler or LeBron James? Paris Hilton or Steven Hawking? I’m an avid fan of Mythbusters (When in doubt, C-4…because if it’s worth doing, it’s worth OVERdoing). Did you see the episode of Fresh Prince of Bel-Air where Will raps the Table of Elements? I thought it was the coolest thing ever; my mom had to hide my dad’s Periodic Table until I stopped mimicking that scene (she was not amused…and still worries about me to this day). And if Angelina Jolie says to look into Polymerase Chain Reactions, you can bet your house, your dog, and your car that by the end of the month I’ll know more than you would ever want to know about it.
Displaying and explaining scientific information and ideas in a common area where everyone can participate, rather than only amongst ourselves, will make science more understandable and accessible.
Seeing a familiar, trustworthy face promote science will allow us to accept scientific ideas as common and good, rather than out-of-place and suspicious.
Combine the two, and we’ll see more people embracing science instead of trying to throw it away.
Sunday, February 14, 2010
Oh the Agony of Waiting...
Wednesday, February 10, 2010
Am I crying yet?
This past week Observation of a Nerd posted a blog about Botox. Considering that I have a mother reaching a particular age (that I won’t mention here, you’re welcome, mom) and she’s been rambling about getting a face-lift and not being able to afford it “like those rich celebrities” yada yada, I decided to read it before “mark[ing] as read.” Apparently Botox, by altering the muscles in your face that control frowning can help manipulate your emotions.
Botox is a prescription medicine; it is a purified protein that temporarily improves the look of moderate-to-severe frown lines between the brows. It is administered through a nonsurgical treatment: injections directly into the muscles between the brows. It works by blocking nerve impulses to the injected muscle which prevents activity that causes persistent lines to form. Regardless of whether or not my mom has wrinkles or needs this, mind you is of lesser importance. The experiment however, was incredible. What these scientists did was give randomly chosen participants (at their will) different sentences to spark reactions—sad, angry and happy, to which they measured reaction times. They then gave them Botox treatments and did the same. Apparently, when reading the happy sentences the reaction times did not vary, however sad or angry comments showed a slower reaction time. While it is common that Botox prevents muscular action (as is the point) could it be true that it alters emotional reactions as well. Further, is this a bad thing? I guess the bigger problem is as follows: your reactions are delayed because your muscles are temporarily paralyzed. So you got your Botox, looking 27, working it down the street and a psycho pulls a gun on you. Are you so enthralled with your lack of facial abilities to realize you’re in danger and react properly? (Assuming your firm, youthful new face doesn’t immediately sway your attacker, that is). Rather, a child being kidnapped in your witness…and you don’t realize the danger in the situation until much later. I realize these scenarios may be extreme but who’s to say that’s not the case? Is it worth putting mental functionality on hold to look 23? I don’t think so. I guess I’m “too young” to understand but I don’t see the necessity in injecting your face (of all places!) with something to paralyze your muscles and slow reaction times. I’ll probably re-visit this opinion in about 20 years; let’s see how I react then.
Tuesday, February 9, 2010
The genetics of cancer
These are all questions I found myself wondering last weekend as I worked on capsule slides in the Microbiology lab, while all the cool kids were out getting wasted.
That was when I realized I had found the topic of my second blog post for Senior Seminar.
I also realized I could really use a liquid cocaine shot.
So I started searching for answers as the snow began to pour down outside.
According to this informative website by the National Cancer Institute, “all cancer is genetic”.
What they mean by that is that all cancer arises from mutations in DNA, or altered genes. When the genes that regulate and control a cell are messed up, the cell is unable to stop replicating. It takes many steps, but if subsequent mutations occur and certain conditions are met, the cancerous cell will progress from normal, to malignant (dangerous), to metastatic (spreading).
“Cancer usually arises in a single cell. The cell's progress from normal to malignant to metastatic appears to involve a series of distinct changes in the tumor and its immediate environment, and each is influenced by different sets of genes.”[1]
But disease inheritance is very complex. Altered or damaged genes do not always get expressed in harmful ways. Different mutations, or the same mutation at different locations, will have different effects. Some will be expressed by severe symptoms, some as mild symptoms, and others will not be expressed at all.
As it turns out, cancer can be passed down if that specific damaged or mutated gene (disease-linked gene) gets passed on. If careful records are kept, a family tree mapping the expression of the disease-linked gene can be constructed. This is helpful in determining your chances of inheriting a disease-linked gene.
The good news is, most cancer is NOT inherited.
“Even though all cancer is genetic, just a small portion--perhaps 5 or 10 percent--is inherited.” [1]
This means that out of ten breast cancer patients, only one of them may have a known inherited factor. The other nine also have cancer, but due to unknown factors that are not inherited.
The Human Genome Project has successfully mapped the chemical bases of all 25,000 genes, as well as the spaces between them.
“This information can be used to determine where gene mutations occur in specific diseases.”[1]
For example, here is a chart of disease-linked genes located along the X chromosome.
With Microarray analysis, complete patterns of gene activity can be captured.
“A DNA microarray is a thin-sized chip that has been spotted at fixed locations with thousands of single-stranded DNA fragments corresponding to various genes of interest. A single microarray may contain 10,000 or more spots, each containing pieces of DNA from a different gene. Fluorescent-labeled probe DNA fragments are added to ask if there are any places on the microarray where the probe strands can match and bind.” [1]
I also found that genetic tests for a wide array of disorders, not just cancer, are already widely used. For instance, newborn babies are commonly screened for a variety of disorders with genetic tests.
There are three different genetic test methods:
- Chromosome test – detect changes to whole chromosomes.
- DNA test – examine short stretches of DNA within genes.
- Protein test – look for protein products of genes.
The only downside to genetic testing is that they find mutations, not the disease itself.
For instance, having an altered gene may increase your chances of getting the disease, but that does not mean that you absolutely, positively WILL develop that disease. It is entirely possible that you will live the rest of your life without ever developing that disease, while someone with a non-altered gene does develop it.
If all I did was confuse you more, this slide may help.
All my questions had been answered.
Since alcohol is banned in the dorms, I celebrated by slamming back a glass of Ocean Spray’s Cran-Grape juice and went to bed.
{For the original slideshow by the National Cancer Institute (where I got this information), click here.}
[1] National Cancer Institute website.
Wednesday, February 3, 2010
Legal or Illegal that is the question.
I mean don't get me wrong I have never been a user of drugs and don't ever want to be, but I do know many people who used marijuana and many people who still do use marijuana not just as a recreational drug, but also as a medical drug. I do not condone the use of drugs in any way at all, but for some people this is the only way to relieve some common health issues. Currently there are 14 states that allow the use of medical marijuana and 2 states that have passed laws that favor the use of medical marijuana. Statistically marijuana is one of the safest drugs to use and helps relieve symptoms of many common medical problems such as glaucoma, pain relief, and has shown to be beneficial in the treatment of MS and depression.
Back to the point of marijuana being safe, in 2006 there were 0 reported deaths due to the use of marijuana, and as far as some browsing that I have done on the Internet 0 cases of overdose on marijuana. So that being said, the big question is should this be legal giving all the benefits that this illegal drug may have. Personally I think that it should be legal, but there still needs to be some sort of regulations for the drug. If we can some how find a way to isolate the active ingredient in marijuana that helps with all these different disease and problems we could completely eliminate the need for regulation and medical use of marijuana completely.
My favorite drug just got better
Most of these effects increase as you drink more coffee:
- Less likely to develop Parkinson's,
- Reduces risk of colon and skin cancer,
- Reduces risk of liver cirrhosis,
- Halves the risk of gallstones,
- Counteracts the effects of smoking and heavy drinking on the heart and liver damage,
- Manages asthma and controls attacks,
- Helps manage diabetes (improves insulin sensitivity and glucose metabolism),
- Stops headaches (in my book, this translates to "cures hangovers"),
- Prevents cavities (bitter antibacterial properties),
- Boosts athleticism (greater endurance and performance).
Of course, drinking too much coffee can be a bad thing.
You may be drinking too much coffee if:
- You have increased nervousness,
- Your hand or leg keeps trembling,
- You have a very rapid heartbeat.
I had thought it was impossible to drink "too much" coffee, but about a year ago I found out I was wrong. After a few weeks of waving away my friends' concerns that six cups of coffee was overdoing it, I started to notice that I had the last two symptoms plus a lovely ominous, recurring pain in my chest.
Taking the hint, I quit coffee cold turkey for a whole two weeks. After the first week, my body got used to making its own energy again instead of relying on a constant stream of caffeine, so I no longer thought I was dying. After the second week, all of the symptoms were gone. When I decided to pick up drinking coffee again, I decided it was best to limit myself to three cups a day.
And coffee isn't for everyone. Some people should be very careful about drinking coffee.
People who should avoid or limit coffee:
- Pregant women,
- People with heart conditions
Well, there you go. Now I can get back to killing this last cup of Joe.
Check out this website for the original article.
Witness the Inncredible
Hi, my name is Greg. I am a senior biology major at Ashland University. After graduation I aspire to become a Physician Assistant. Science and particularly physiology have caught my interest. Since, I am a big time sports fan I think it is absolutely amazing how trillions of cells can work together to perform such a task as to running 100m in 9.58 seconds. Or how about watching Vince Carter jump over a seven foot two French center in the 2000 Olympics and “throw the hammer down”. Watching the human body achieve what many people thought once was impossible shows how truly remarkable the human body is. In order to understand how humans and organisms became to be, one must have to look at single celled organism to understand how life on Earth evolved into something so perfectly designed for life. As Darwin could explain but not prove, new species did arrive from pre-existing life. Darwin also explained how species evolved and became better suited to live in certain environments. Life on Earth began as a singled celled organism and now has given rise to incredible minds and spectacular athletes. Here is a video of Vince Carter dunking a basketball on a 7’2 man.